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LRP1 抗体 (AA 4486-4535)

The 兔 多克隆 anti-LRP1 antibody is suitable to detect LRP1 in samples from 人 和 小鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1533132
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LRP1 抗体 (AA 4486-4535) (ABIN1533132)

抗原

See all LRP1 抗体
LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

适用

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人, 小鼠

宿主

  • 124
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兔

克隆类型

  • 84
  • 81
多克隆

标记

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This LRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
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    AA 4486-4535

    原理

    LRP1 Antibody

    特异性

    LRP1 Polyclonal Antibody detects endogenous levels of LRP1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CD91. AA range:4486-4535

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

    别名

    CD91

    背景

    Synonyms: LRP1; A2MR; APR; Prolow-density lipoprotein receptor-related protein 1; LRP-1; Alpha-2-macroglobulin receptor; A2MR; Apolipoprotein E receptor; APOER; CD antigen CD91

    Background: This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015],

    Gene Name: LRP1

    Protein Name: Prolow-density lipoprotein receptor-related protein 1

    分子量

    504 kDa

    基因ID

    4035

    OMIM

    107770

    UniProt

    Q07954

    途径

    Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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