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IRS1 抗体 (AA 279-328)

The 兔 多克隆 anti-IRS1 antibody is suitable to detect IRS1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF, IHC (p) 和 ICC.
产品编号 ABIN483524
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IRS1 抗体 (AA 279-328) (ABIN483524)

抗原

See all IRS1 抗体
IRS1 (Insulin Receptor Substrate 1 (IRS1))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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  • 48
多克隆

标记

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This IRS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 279-328

    原理

    IRS-1 Antibody

    特异性

    IRS-1 Polyclonal Antibody detects endogenous levels of IRS-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human IRS-1. AA range:279-328

    亚型

    IgG
  • 应用备注

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    IRS1 (Insulin Receptor Substrate 1 (IRS1))

    别名

    IRS-1

    背景

    Synonyms: IRS1, Insulin receptor substrate 1, IRS-1

    Background: H2A histone family member X(H2AFX) Homo sapiens Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

    Gene Name: IRS1

    Protein Name: Insulin receptor substrate 1

    分子量

    131 kDa

    OMIM

    125853

    UniProt

    P35568

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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