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HNF4A 抗体 (AA 280-329)

This 兔 多克隆 antibody specifically detects HNF4A in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1532895
发货至: 中国
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Quick Overview for HNF4A 抗体 (AA 280-329) (ABIN1532895)

抗原

See all HNF4A 抗体
HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

适用

  • 151
  • 66
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  • 5
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  • 1
人, 大鼠, 小鼠

宿主

  • 132
  • 21
  • 2
兔

克隆类型

  • 90
  • 65
多克隆

标记

  • 79
  • 9
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  • 5
  • 5
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  • 5
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  • 1
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  • 1
  • 1
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This HNF4A antibody is un-conjugated

应用范围

  • 121
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  • 23
  • 15
  • 15
  • 11
  • 10
  • 10
  • 4
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 13
    • 10
    • 9
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    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 280-329

    原理

    HNF-4α Antibody

    特异性

    HNF-4α Polyclonal Antibody detects endogenous levels of HNF-4α protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human HNF4 alpha. AA range:280-329

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

    别名

    HNF4 alpha

    背景

    Synonyms: HNF4A, HNF4, NR2A1, TCF14, Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4

    Background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],

    Gene Name: HNF4A

    Protein Name: Hepatocyte nuclear factor 4-alpha

    分子量

    52 kDa

    基因ID

    3172

    OMIM

    125850

    UniProt

    P41235

    途径

    AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
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