IL13 Receptor alpha 1 抗体 (AA 371-420)
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Quick Overview for IL13 Receptor alpha 1 抗体 (AA 371-420) (ABIN1532687)
抗原
See all IL13 Receptor alpha 1 (IL13RA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 371-420
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原理
- IL-13Rα1 Antibody
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特异性
- IL-13Rα1 Polyclonal Antibody detects endogenous levels of IL-13Rα1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human IL-13R/CD213 alpha1. AA range:371-420
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
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别名
- IL-13R/CD213 Alpha1
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背景
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Synonyms: IL13RA1, IL13R, IL13RA, Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19, CD antigen CD213a1
Background: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008],
Gene Name: IL13RA1
Protein Name: Interleukin-13 receptor subunit alpha-1
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分子量
- 48 kDa
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基因ID
- 3597
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OMIM
- 300119
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UniProt
- P78552
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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