Survivin 抗体 (C-Term)
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Quick Overview for Survivin 抗体 (C-Term) (ABIN1532414)
抗原
See all Survivin (BIRC5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 86-135, C-Term
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原理
- Survivin Antibody(C-terminal )
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特异性
- Survivin Polyclonal Antibody detects endogenous levels of Survivin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Survivin. AA range:86-135
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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别名
- Survivin
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背景
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Synonyms: BIRC5, API4, IAP4, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin
Background: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, butThis gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
Gene Name: BIRC5
Protein Name: Baculoviral IAP repeat-containing protein 5
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分子量
- 16 kDa
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基因ID
- 332
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OMIM
- 603352
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UniProt
- O15392
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途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原
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