Rhodopsin 抗体 (AA 299-348)
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Quick Overview for Rhodopsin 抗体 (AA 299-348) (ABIN1532407)
抗原
See all Rhodopsin (RHO) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 299-348
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原理
- Rhodopsin Antibody
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特异性
- Rhodopsin Polyclonal Antibody detects endogenous levels of Rhodopsin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Rhodopsin. AA range:299-348
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Rhodopsin in plasma from patients with diabetic retinopathy - development and validation of digital ELISA by Single Molecule Array (Simoa) technology." in: Journal of immunological methods, Vol. 446, pp. 60-69, (2017) (PubMed).
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- Rhodopsin (RHO)
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别名
- Rhodopsin
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物质类
- Chemical
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背景
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Synonyms: RHO, OPN2, Rhodopsin, Opsin-2
Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008],
Gene Name: RHO
Protein Name: Rhodopsin
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分子量
- 39 kDa
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基因ID
- 6010
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OMIM
- 180380
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UniProt
- P08100
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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