Girdin 抗体 (pSer1417)
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北京 101111
Quick Overview for Girdin 抗体 (pSer1417) (ABIN1532146)
抗原
See all Girdin (CCDC88A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1383-1432, pSer1417
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原理
- Girdin (phospho Ser1417) Antibody
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特异性
- Phospho-Girdin (S1417) Polyclonal Antibody detects endogenous levels of Girdin protein only when phosphorylated at S1417.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Girdin around the phosphorylation site of Ser1417. AA range:1383-1432
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1401-1500) antibody
CCDC88A 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pTyr1765) antibodyCCDC88A 适用: 人 IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1571-1870) antibodyCCDC88A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1425-1475) antibodyCCDC88A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pSer1417) antibodyCCDC88A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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别名
- Girdin
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背景
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Synonyms: CCDC88A, APE, GRDN, KIAA1212, Girdin, Akt phosphorylation enhancer, APE, Coiled-coil domain-containing protein 88A, G alpha-interacting vesicle-associated protein, GIV, Girders of actin filament, Hook-related protein 1, HkRP1
Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Gene Name: CCDC88A
Protein Name: Girdin
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分子量
- 216 kDa
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基因ID
- 55704
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OMIM
- 609736
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UniProt
- Q3V6T2
抗原
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