BRCA1 抗体 (pSer1457)
Quick Overview for BRCA1 抗体 (pSer1457) (ABIN1532128)
抗原
See all BRCA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 1423-1472, pSer1457
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特异性
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BRCA1 (Phospho-Ser1457) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1457.
PhosphorylationH:S1457
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纯化方法
 - The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
 - > 95 %
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免疫原
 - The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1457.
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亚型
 - IgG
 
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应用备注
 - WB: 1:500~1:1000 ELISA: 1:1000
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说明
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Unigene-Number: Hs.194143 (NCBI Gene Symbol: BRCA1)
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 mg/mL
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缓冲液
 - phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
 - Sodium azide
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注意事项
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Stable at -20°C for at least 1 year.
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有效期
 - 12 months
 
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- BRCA1 (Breast Cancer 1 (BRCA1))
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别名
 - BRCA1
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背景
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Synonyms: BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1
NCBI Gene Symbol: BRCA1
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分子量
 - 207 kDa
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基因ID
 - 672
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OMIM
 - 113705
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UniProt
 - P38398
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途径
 - Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
 
抗原
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