Src 抗体 (pTyr529)
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北京 101111
Quick Overview for Src 抗体 (pTyr529) (ABIN1531972)
抗原
See all Src 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 487-536, pTyr529
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原理
- c-Src (phospho Tyr529) Antibody
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特异性
- Phospho-c-Src (Y529) Polyclonal Antibody detects endogenous levels of c-Src protein only when phosphorylated at Y529.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr529. AA range:487-536
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亚型
- IgG
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anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibody
Src 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 17AT28 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52), (N-Term) antibodySrc 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB41141 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodySrc 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodyKD Validated Src 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB985 unconjugated Recombinant Antibody
anti-Proto-oncogene tyrosine-protein kinase Src (Src) antibodyKO Validated Src 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibodySrc 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 24-52) antibodySrc 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 397-424) antibodySrc 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB21492 unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (pTyr529) antibodySrc 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Proto-oncogene tyrosine-protein kinase Src (Src) (AA 1-90) antibodySrc 适用: 人 IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1B9 unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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别名
- Src
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背景
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Synonyms: SRC, SRC1, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src
Background: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth.The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: SRC
Protein Name: Proto-oncogene tyrosine-protein kinase Src
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分子量
- 59 kDa
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基因ID
- 6714
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OMIM
- 190090
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UniProt
- P12931
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途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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