BRCA1 抗体 (pSer1423)
Quick Overview for BRCA1 抗体 (pSer1423) (ABIN1531790)
抗原
See all BRCA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1391-1440, pSer1423
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特异性
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BRCA1 (Phospho-Ser1423) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1423.
PhosphorylationH:S1423 R:S1380
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1423.
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亚型
- IgG
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应用备注
- IHC: 1:50~1:100 ELISA: 1:4000
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说明
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Unigene-Number: Hs.194143 (NCBI Gene Symbol: BRCA1)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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- BRCA1 (Breast Cancer 1 (BRCA1))
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别名
- BRCA1
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背景
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Synonyms: BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1
NCBI Gene Symbol: BRCA1
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分子量
- 207 kDa
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基因ID
- 672
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OMIM
- 113705
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UniProt
- P38398
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途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
抗原
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