RECQL2 抗体 (pSer1141)
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Quick Overview for RECQL2 抗体 (pSer1141) (ABIN1531762)
抗原
See all RECQL2 (WRN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1107-1156, pSer1141
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原理
- WRN (phospho Ser1141) Antibody
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特异性
- Phospho-WRN (S1141) Polyclonal Antibody detects endogenous levels of WRN protein only when phosphorylated at S1141.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Werner Syndrome Helicase around the phosphorylation site of Ser1141. AA range:1107-1156
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亚型
- IgG
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anti-Werner syndrome RecQ like helicase (WRN) (AA 787-816) antibody
WRN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17383 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibodyWRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (Center) antibodyWRN 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (C-Term) antibodyWRN 适用: 人 WB, FACS, IP 宿主: 兔 Monoclonal BLR333M unconjugated Recombinant Antibody
anti-Werner syndrome RecQ like helicase (WRN) antibodyWRN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibodyWRN 适用: 人 WB 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) antibodyWRN 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal 195C unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (C-Term) antibodyWRN 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1223-1432) antibodyWRN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 400-450) antibodyWRN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
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别名
- Werner Syndrome Helicase
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背景
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Synonyms: WRN; RECQ3; RECQL2; Werner syndrome ATP-dependent helicase; DNA helicase; RecQ-like type 3; RecQ3; Exonuclease WRN; RecQ protein-like 2
Background: Werner syndrome RecQ like helicase(WRN) Homo sapiens This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [provided by RefSeq, Jul 2008],
Gene Name: WRN
Protein Name: Werner syndrome ATP-dependent helicase
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分子量
- 162 kDa
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基因ID
- 7486
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OMIM
- 114500
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UniProt
- Q14191
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途径
- DNA Damage Repair
抗原
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