MUC1 抗体 (pTyr1229)
Our Local Distributor
北京 101111
Quick Overview for MUC1 抗体 (pTyr1229) (ABIN1531735)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1201-1250, pTyr1229
-
原理
- Mucin 1 (phospho Tyr1229) Antibody
-
特异性
- Phospho-Mucin 1 (Y1229) Polyclonal Antibody detects endogenous levels of Mucin 1 protein only when phosphorylated at Y1229.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human CD227/MUC1 around the phosphorylation site of Tyr1229. AA range:1201-1250
-
亚型
- IgG
-
-
anti-Mucin 1 (MUC1) antibody
MUC1 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 小鼠 Monoclonal MUC1-955 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人, 小鼠 IHC, WB 宿主: 小鼠 Monoclonal MUC1-520 unconjugated
anti-Mucin 1 (MUC1) (AA 66-175) antibodyMUC1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3B10B4 unconjugated
anti-Mucin 1 (MUC1) (AA 1182-1255) antibodyMUC1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 410-525) antibodyMUC1 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 474-630) antibodyMUC1 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Mucin 1 (MUC1) (AA 404-655) antibodyMUC1 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 1098-1255) antibodyMUC1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人, 小鼠 IHC, WB, ELISA 宿主: 兔 Monoclonal MUC1-2818R unconjugated Recombinant Antibody
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- MUC1 (Mucin 1 (MUC1))
-
别名
- CD227/MUC1
-
背景
-
Synonyms: MUC1, PUM, Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated ep
Background: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp
Gene Name: MUC1
Protein Name: Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha)Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)], CA 15-3, CA15 3, CA 15.3 , CA15-3, CA15.3
-
分子量
- 122 kDa
-
基因ID
- 4582
-
OMIM
- 113720
-
UniProt
- P15941
-
途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
-
