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HRH1 抗体 (pSer398)

The 兔 多克隆 anti-HRH1 antibody (ABIN1531653) specifically detects HRH1 in ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1531653
发货至: 中国
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Quick Overview for HRH1 抗体 (pSer398) (ABIN1531653)

抗原

See all HRH1 抗体
HRH1 (Histamine Receptor H1 (HRH1))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

  • 69
  • 6
多克隆

标记

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This HRH1 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 364-413, pSer398

    原理

    Histamine H1 Receptor (phospho Ser398) Antibody

    特异性

    Phospho-Histamine H1 Receptor (S398) Polyclonal Antibody detects endogenous levels of Histamine H1 Receptor protein only when phosphorylated at S398.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Histamine H1 Receptor around the phosphorylation site of Ser398. AA range:364-413

    亚型

    IgG
  • 应用备注

    IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HRH1 (Histamine Receptor H1 (HRH1))

    别名

    Histamine H1 Receptor

    背景

    Synonyms: HRH1, Histamine H1 receptor, H1R, HH1R

    Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4.The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by Ref

    Gene Name: HRH1

    Protein Name: Histamine H1 receptor

    分子量

    55 kDa

    基因ID

    3269

    OMIM

    600167

    UniProt

    P35367

    途径

    Regulation of Carbohydrate Metabolic Process
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