HRH1 抗体 (pSer398)
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Quick Overview for HRH1 抗体 (pSer398) (ABIN1531653)
抗原
See all HRH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 364-413, pSer398
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原理
- Histamine H1 Receptor (phospho Ser398) Antibody
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特异性
- Phospho-Histamine H1 Receptor (S398) Polyclonal Antibody detects endogenous levels of Histamine H1 Receptor protein only when phosphorylated at S398.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Histamine H1 Receptor around the phosphorylation site of Ser398. AA range:364-413
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亚型
- IgG
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应用备注
- IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HRH1 (Histamine Receptor H1 (HRH1))
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别名
- Histamine H1 Receptor
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背景
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Synonyms: HRH1, Histamine H1 receptor, H1R, HH1R
Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4.The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by Ref
Gene Name: HRH1
Protein Name: Histamine H1 receptor
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分子量
- 55 kDa
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基因ID
- 3269
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OMIM
- 600167
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UniProt
- P35367
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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