Cytokeratin 18 抗体 (pSer52)
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北京 101111
Quick Overview for Cytokeratin 18 抗体 (pSer52) (ABIN1531567)
抗原
See all Cytokeratin 18 (KRT18) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-70, pSer52
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原理
- Cytokeratin 18 (phospho Ser52) Antibody
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特异性
- Phospho-Cytokeratin 18 (S52) Polyclonal Antibody detects endogenous levels of Cytokeratin 18 protein only when phosphorylated at S52.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Keratin 18 around the phosphorylation site of Ser52. AA range:21-70
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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别名
- Keratin 18
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背景
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Synonyms: KRT18, CYK18, PIG46, Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18
Background: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: KRT18
Protein Name: Keratin type I cytoskeletal 18
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分子量
- 48 kDa
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基因ID
- 3875
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OMIM
- 148070
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UniProt
- P05783
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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