ACLY 抗体 (pSer454)
Our Local Distributor
北京 101111
Quick Overview for ACLY 抗体 (pSer454) (ABIN1531422)
抗原
See all ACLY 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 420-469, pSer454
-
原理
- ATP-citrate synthase (phospho Ser455) Antibody
-
特异性
- Phospho-ATP-citrate synthase (S455) Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein only when phosphorylated at S455.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human ATP-Citrate Lyase around the phosphorylation site of Ser454. AA range:420-469
-
亚型
- IgG
-
-
anti-ATP Citrate Lyase (ACLY) (AA 306-502) antibody
ACLY 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5F8D11 unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 752-1101) antibodyACLY 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (pSer455) antibodyACLY 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 1-180) antibodyACLY 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 1-180) antibodyACLY 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 5I2 unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyACLY 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 4-265) antibodyACLY 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 306-502) antibodyACLY 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (C-Term) antibodyACLY 适用: 人, 小鼠 WB, FACS, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyACLY 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Monoclonal 3A5 unconjugated Recombinant Antibody
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- ACLY (ATP Citrate Lyase (ACLY))
-
别名
- ATP-Citrate Lyase
-
背景
-
Synonyms: ACLY, ATP-citrate synthase, ATP-citrate, pro-S-)-lyase, ACL, Citrate cleavage enzyme
Background: ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],
Gene Name: ACLY
Protein Name: ATP-citrate synthase
-
分子量
- 120 kDa
-
基因ID
- 47
-
OMIM
- 108728
-
UniProt
- P53396
-
途径
- Warburg Effect
抗原
-
