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FLT1 抗体 (pTyr1333)

This 兔 多克隆 antibody specifically detects FLT1 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1531410
发货至: 中国
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Quick Overview for FLT1 抗体 (pTyr1333) (ABIN1531410)

抗原

See all FLT1 抗体
FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

适用

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人, 大鼠, 小鼠

宿主

  • 209
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兔

克隆类型

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  • 80
多克隆

标记

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This FLT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 1289-1338, pTyr1333

    原理

    Flt-1/VEGFR1 (phospho Tyr1333) Antibody

    特异性

    Phospho-Flt-1 (Y1333) Polyclonal Antibody detects endogenous levels of Flt-1 protein only when phosphorylated at Y1333.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human VEGFR1 around the phosphorylation site of Tyr1333. AA range:1289-1338

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

    别名

    VEGFR1

    背景

    Synonyms: FLT1, FLT, FRT, VEGFR1, Vascular endothelial growth factor receptor 1, VEGFR-1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor

    Background: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009],

    Gene Name: FLT1

    Protein Name: Vascular endothelial growth factor receptor 1

    分子量

    150 kDa

    基因ID

    2321

    OMIM

    165070

    UniProt

    P17948

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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