Insulin Receptor 抗体 (pTyr1355)
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Quick Overview for Insulin Receptor 抗体 (pTyr1355) (ABIN1531327)
抗原
See all Insulin Receptor (INSR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1326-1375, pTyr1355
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原理
- Insulin R (phospho Tyr1355) Antibody
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特异性
- Phospho-Insulin R (Y1355) Polyclonal Antibody detects endogenous levels of Insulin R protein only when phosphorylated at Y1355.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human IR around the phosphorylation site of Tyr1355. AA range:1326-1375
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亚型
- IgG
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anti-Insulin Receptor (INSR) antibody
INSR 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-Insulin Receptor (INSR) (AA 1024-1298) antibodyINSR 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyINSR 适用: 人, 小鼠, 大鼠, 猴, 犬, Pig, 马, Cow, 豚鼠, 兔, 绵羊, Hamster, 小鸡, Avian, Cat, 驴, 山羊 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyKO Validated INSR 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1101-1372) antibodyINSR 适用: 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1027-1364) antibodyINSR 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 51-150) antibodyINSR 适用: 人 WB, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1325-1358) antibodyINSR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50340 unconjugated
anti-Insulin Receptor (INSR) (pTyr1355) antibodyINSR 适用: 人, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1023-1298) antibodyINSR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Insulin Receptor (INSR)
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背景
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Synonyms: INSR, Insulin receptor, IR, CD antigen CD220
Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Gene Name: INSR
Protein Name: Insulin receptor
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分子量
- 156 kDa
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基因ID
- 3643
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OMIM
- 125853
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UniProt
- P06213
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途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
抗原
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