EGFR 抗体 (pTyr1016)
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Quick Overview for EGFR 抗体 (pTyr1016) (ABIN1531312)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 986-1035, pTyr1016
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原理
- EGFR (phospho Tyr1016) Antibody
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特异性
- Phospho-EGFR (Y1016) Polyclonal Antibody detects endogenous levels of EGFR protein only when phosphorylated at Y1016.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1016. AA range:986-1035
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亚型
- IgG
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anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5G9B5 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893), (Mutant) antibodyEGFR 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5G9B5 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibodyEGFR 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A6F12 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibodyEGFR 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1163-1191), (C-Term) antibodyEGFR 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 688CT33-1-3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibodyEGFR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5E10D3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 小鸡, 犬, 马, 兔, 豚鼠, Avian, Cat, 驴, 山羊, Hamster, 绵羊 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) antibodyKD Validated EGFR 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4395 unconjugated Recombinant Antibody
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR 适用: 人, 大鼠 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 344-492) antibodyEGFR 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal GFR-2341 unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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别名
- EGFR
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背景
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Synonyms: EGFR, ERBB, ERBB1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],
Gene Name: EGFR
Protein Name: Epidermal growth factor receptor
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分子量
- 134 kDa
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基因ID
- 1956
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OMIM
- 131550
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UniProt
- P00533
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
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