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Calnexin 抗体 (pSer583)

This 兔 多克隆 antibody specifically detects Calnexin in WB, IHC, IF 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1531305
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Calnexin 抗体 (pSer583) (ABIN1531305)

抗原

See all Calnexin (CANX) 抗体
Calnexin (CANX)

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Calnexin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

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    AA 543-592, pSer583

    原理

    Calnexin (phospho Ser583) Antibody

    特异性

    Phospho-Calnexin (S583) Polyclonal Antibody detects endogenous levels of Calnexin protein only when phosphorylated at S583.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Calnexin around the phosphorylation site of Ser583. AA range:543-592

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Calnexin (CANX)

    别名

    Calnexin

    背景

    Synonyms: CANX, Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90

    Background: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],

    Gene Name: CANX

    Protein Name: Calnexin

    分子量

    67 kDa

    基因ID

    821

    OMIM

    114217

    UniProt

    P27824

    途径

    MAPK Pathway, Thyroid Hormone Synthesis
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