PRAS40 抗体 (pSer1, pThr246)
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Quick Overview for PRAS40 抗体 (pSer1, pThr246) (ABIN1531296)
抗原
See all PRAS40 (AKT1S1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 207-256, pSer1, pThr246
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原理
- PRAS40 (phospho Thr246) Antibody
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特异性
- Phospho-PRAS40 (T246) Polyclonal Antibody detects endogenous levels of PRAS40 protein only when phosphorylated at T246.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Akt1 S1 around the phosphorylation site of Thr246. AA range:207-256
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
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别名
- Akt1 S1
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背景
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Synonyms: AKT1S1, PRAS40, Proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate
Background: AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008],
Gene Name: AKT1S1
Protein Name: Proline-rich AKT1 substrate 1
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分子量
- 27 kDa
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基因ID
- 84335
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OMIM
- 610221
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UniProt
- Q96B36
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect
抗原
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