IKK-alpha /IKK-beta 抗体 (pSer180, pSer181)
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北京 101111
Quick Overview for IKK-alpha /IKK-beta 抗体 (pSer180, pSer181) (ABIN1531284)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-200, pSer180, pSer181
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原理
- IKKα/β (phospho Ser180/181) Antibody
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特异性
- Phospho-IKKα/β (S180/181) Polyclonal Antibody detects endogenous levels of IKKα/β protein only when phosphorylated at S180/181.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta around the phosphorylation site of Ser180/181. AA range:151-200
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亚型
- IgG
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anti-IKK-alpha /IKK-beta (pSer176), (pSer180) antibody
适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (pSer176), (pSer177) antibody适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (pSer180), (pSer181) antibody适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (AA 151-250) antibody适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (AA 155-184) antibody适用: 人 WB 宿主: 兔 Polyclonal RB40935 unconjugated
anti-IKK-alpha /IKK-beta (pSer176), (pSer177) antibody适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (pSer180), (pSer181) antibody适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IKK-alpha /IKK-beta (Lys6) antibody适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells." in: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014) (PubMed).
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- IKK-alpha /IKK-beta
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别名
- IKK-alpha/beta
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背景
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Synonyms: CHUK, IKKA, TCF16, Inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, IKK1, Nuclear factor NF-kappa-B
Background: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008],
Gene Name: CHUK/IKBKB
Protein Name: Inhibitor of nuclear factor kappa-B kinase subunit alpha
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分子量
- 84 kDa
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基因ID
- 1147, 3551
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OMIM
- 600664
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UniProt
- O15111
抗原
-
