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IKK-alpha /IKK-beta 抗体 (pSer180)

Cited in 1 publication. This 兔 多克隆 anti-IKK-alpha /IKK-beta antibody specifically detects IKK-alpha /IKK-beta in WB, IHC 和 ELISA. The antibody is reactive with 小鼠, 人 和 大鼠 samples.
产品编号 ABIN1531284
发货至: 中国
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Quick Overview for IKK-alpha /IKK-beta 抗体 (pSer180) (ABIN1531284)

抗原

IKK-alpha /IKK-beta

适用

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  • 1
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小鼠, 人, 大鼠

宿主

  • 88

克隆类型

  • 70
  • 18
多克隆

标记

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This IKK-alpha /IKK-beta antibody is un-conjugated

应用范围

  • 59
  • 41
  • 40
  • 22
  • 17
  • 11
  • 11
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  • 10
  • 10
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 151-200, pSer180

    特异性

    IKK-alpha/beta (Phospho-Ser180/181) Antibody detects endogenous levels of IKK-alpha/beta only when phosphorylated at Ser180/181.

    PhosphorylationH:S180/S181 M:S180/S181 R:S180/S181

    纯化方法

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta around the phosphorylation site of Ser180/181.

    亚型

    IgG
  • 应用备注

    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

    说明

    Unigene-Number: Hs.198998, Hs.656458 (NCBI Gene Symbol: CHUK)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable at -20°C for at least 1 year.

    有效期

    12 months
  • Hsieh, Hsiao, Hsu, Wang, Sheu: "PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells." in: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014) (PubMed).

  • 抗原

    IKK-alpha /IKK-beta

    别名

    IKK-alpha/beta

    背景

    Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IkappaB kinase, IkBKA, IKK-A, IKK-alpha, IKK1, IKKA, Inhibitor of nuclear factor kappa-B kinase alpha subunit, kinase IKK-alpha, NFKBIKA, Nuclear factor NFkapp

    NCBI Gene Symbol: CHUK

    分子量

    84 kDa

    基因ID

    1147, 3551

    OMIM

    600664

    UniProt

    O15111, O14920
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