IKK-alpha /IKK-beta 抗体 (pSer180)
Quick Overview for IKK-alpha /IKK-beta 抗体 (pSer180) (ABIN1531284)
抗原
适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 151-200, pSer180
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                                            特异性
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                        IKK-alpha/beta (Phospho-Ser180/181) Antibody detects endogenous levels of IKK-alpha/beta only when phosphorylated at Ser180/181. PhosphorylationH:S180/S181 M:S180/S181 R:S180/S181 
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                                            纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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                                            纯度
- > 95 %
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                                            免疫原
- The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta around the phosphorylation site of Ser180/181.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
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                                            说明
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                        Unigene-Number: Hs.198998, Hs.656458 (NCBI Gene Symbol: CHUK) 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 mg/mL
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                                            缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Stable at -20°C for at least 1 year.
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                                            有效期
- 12 months
 
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    - 
                                            : "PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells."    in: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014)         (PubMed).        
 
 
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                                            : "PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells."    in: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014)         (PubMed).        
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    - IKK-alpha /IKK-beta
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                                            别名
- IKK-alpha/beta
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                                            背景
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                        Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IkappaB kinase, IkBKA, IKK-A, IKK-alpha, IKK1, IKKA, Inhibitor of nuclear factor kappa-B kinase alpha subunit, kinase IKK-alpha, NFKBIKA, Nuclear factor NFkapp NCBI Gene Symbol: CHUK 
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                                            分子量
- 84 kDa
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                                            基因ID
- 1147, 3551
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                                            OMIM
- 600664
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                                            UniProt
- O15111, O14920
 抗原
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