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FAK 抗体 (pTyr576)

This 兔 多克隆 antibody specifically detects FAK in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1531272
发货至: 中国
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Room 801-803
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Quick Overview for FAK 抗体 (pTyr576) (ABIN1531272)

抗原

See all FAK (PTK2) 抗体
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This FAK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
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    AA 542-591, pTyr576

    原理

    FAK (phospho Tyr576) Antibody

    特异性

    Phospho-FAK (Y576) Polyclonal Antibody detects endogenous levels of FAK protein only when phosphorylated at Y576.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FAK around the phosphorylation site of Tyr576. AA range:542-591

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    别名

    FAK

    背景

    Synonyms: PTK2, FAK, FAK1, Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK

    Background: protein tyrosine kinase 2(PTK2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015],

    Gene Name: PTK2

    Protein Name: Focal adhesion kinase 1

    分子量

    119 kDa

    基因ID

    5747

    OMIM

    600758

    UniProt

    Q05397

    途径

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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