CSK 抗体 (pSer364)
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北京 101111
Quick Overview for CSK 抗体 (pSer364) (ABIN1531264)
抗原
See all CSK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-379, pSer364
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原理
- Csk (phospho Ser364) Antibody
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特异性
- Phospho-Csk (S364) Polyclonal Antibody detects endogenous levels of Csk protein only when phosphorylated at S364.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Csk around the phosphorylation site of Ser364. AA range:330-379
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亚型
- IgG
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anti-C-Src tyrosine Kinase (CSK) (AA 1-100) antibody
CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-C-Src tyrosine Kinase (CSK) (C-Term) antibodyVerified CSK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 2-204) antibodyCSK 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyKD Validated CSK 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1920 unconjugated Recombinant Antibody
anti-C-Src tyrosine Kinase (CSK) (AA 67-101), (N-Term) antibodyCSK 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50568 unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibodyCSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 1-200) antibodyCSK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibodyCSK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase." in: Scientific reports, Vol. 3, pp. 926, (2013) (PubMed).
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- CSK (C-Src tyrosine Kinase (CSK))
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别名
- Csk
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背景
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Synonyms: CSK, Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL
Background: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Mainly cytoplasmic, also present in lipid rafts.,subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.,tissue specificity:Expressed in lung and macrophages.,
Gene Name: CSK
Protein Name: Tyrosine-protein kinase CSK
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分子量
- 50 kDa
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基因ID
- 1445
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OMIM
- 124095
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UniProt
- P41240
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途径
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
抗原
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