TDG 抗体
Quick Overview for TDG 抗体 (ABIN1526109)
抗原
See all TDG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein-A affinity chromatography
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亚型
- IgG1
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anti-Thymine-DNA Glycosylase (TDG) (AA 141-410) antibody
TDG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 1-410) antibodyTDG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (Internal Region) antibodyTDG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) antibodyTDG 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 1-410) antibodyTDG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) antibodyTDG 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 281-310), (C-Term) antibodyTDG 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19894 unconjugated
anti-Thymine-DNA Glycosylase (TDG) (AA 81-110), (N-Term) antibodyTDG 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19893 unconjugated
anti-Thymine-DNA Glycosylase (TDG) (Center) antibodyTDG 适用: 人, 小鼠, 大鼠, Cow WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % Glycerol, 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- TDG (Thymine-DNA Glycosylase (TDG))
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别名
- TDG
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背景
- G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. Several bacterial proteins have strong sequence homology with this protein. The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.Synonyms: G/T mismatch-specific thymine DNA glycosylase
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途径
- DNA Damage Repair, Chromatin Binding
抗原
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