MYD88 抗体 (AA 171-220)
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北京 101111
Quick Overview for MYD88 抗体 (AA 171-220) (ABIN1453590)
抗原
See all MYD88 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 171-220
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原理
- MyD88 Antibody
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特异性
- MyD88 Polyclonal Antibody detects endogenous levels of MyD88 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220
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亚型
- IgG
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anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 201-296) antibody
MYD88 适用: 小鼠 WB, IP, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 44-264) antibodyMYD88 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (Internal Region) antibodyVerified MYD88 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 32-265) antibodyMYD88 适用: 小鼠 IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 136-164) antibodyMYD88 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21010 unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibodyMYD88 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) antibodyKO Validated MYD88 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) antibodyKD Validated MYD88 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB240 unconjugated Recombinant Antibody
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 大鼠 IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunocytochemistry: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "β-Sitosterol modulates TLR4 receptor expression and intracellular MyD88-dependent pathway activation in J774A.1 murine macrophages." in: Cellular immunology, Vol. 285, Issue 1-2, pp. 76-83, (2014) (PubMed).
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- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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别名
- MyD88
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背景
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Synonyms: MYD88, Myeloid differentiation primary response protein MyD88
Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Gene Name: MyD88
Protein Name: Myeloid differentiation primary response protein MyD88
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分子量
- 33 kDa
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基因ID
- 4615
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OMIM
- 602170
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UniProt
- Q99836
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途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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