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MICA 抗体 (AA 204-253)

The 兔 多克隆 anti-MICA antibody (ABIN1453404) specifically detects MICA in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN1453404
发货至: 中国
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Quick Overview for MICA 抗体 (AA 204-253) (ABIN1453404)

抗原

See all MICA 抗体
MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

适用

  • 117
  • 18
  • 14
  • 12
  • 12
  • 9
  • 7
  • 4
  • 4
  • 1
人

宿主

  • 57
  • 45
  • 17
兔

克隆类型

  • 66
  • 50
  • 2
多克隆

标记

  • 67
  • 13
  • 9
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MICA antibody is un-conjugated

应用范围

  • 66
  • 41
  • 39
  • 26
  • 19
  • 14
  • 11
  • 9
  • 8
  • 6
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 204-253

    原理

    HLA Class I Antibody

    特异性

    The antibody detects endogenous HLA Class I protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human HLA Class I. AA range:204-253

    亚型

    IgG
  • 应用备注

    WB 1:500-2000, ELISA 1:10000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

    别名

    HLA Class I

    背景

    Synonyms: HLA-A HLAA

    Background: HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney trans

    Gene Name: HLA-A HLAA

    Protein Name: major histocompatibility complex, class I

    分子量

    40 kDa

    OMIM

    142800

    UniProt

    P04439

    途径

    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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