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DDR1 抗体 (AA 749-798)

The 兔 多克隆 anti-DDR1 antibody (ABIN1453188) specifically detects DDR1 in WB 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1453188
发货至: 中国
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Quick Overview for DDR1 抗体 (AA 749-798) (ABIN1453188)

抗原

See all DDR1 抗体
DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

适用

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人, 大鼠, 小鼠

宿主

  • 119
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兔

克隆类型

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多克隆

标记

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This DDR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 749-798

    原理

    DDR1 Antibody

    特异性

    DDR1 Polyclonal Antibody detects endogenous levels of DDR1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human DDR1. AA range:749-798

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

    别名

    DDR1

    背景

    Synonyms: DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2,

    Background: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism.The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],

    Gene Name: DDR1

    Protein Name: Epithelial discoidin domain-containing receptor 1

    分子量

    101 kDa

    基因ID

    780

    OMIM

    600408

    UniProt

    Q08345

    途径

    RTK signaling, Smooth Muscle Cell Migration
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