SETMAR 抗体 (AA 350-400)
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北京 101111
Quick Overview for SETMAR 抗体 (AA 350-400) (ABIN1451979)
抗原
See all SETMAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-400
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原理
- SETMAR Antibody
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特异性
- SETMAR Polyclonal Antibody detects endogenous levels of SETMAR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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别名
- SETMAR
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背景
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Synonyms: SETMAR, Histone-lysine N-methyltransferase SETMAR, SET domain and mariner transposase fusion gene-containing protein, HsMar1, Metnase
Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
Gene Name: SETMAR
Protein Name: Histone-lysine N-methyltransferase SETMAR
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分子量
- 76 kDa
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基因ID
- 6419
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OMIM
- 609834
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UniProt
- Q53H47
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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