Manic Fringe 抗体 (AA 61-110)
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北京 101111
Quick Overview for Manic Fringe 抗体 (AA 61-110) (ABIN1451061)
抗原
See all Manic Fringe (MFNG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-110
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原理
- Manic Fringe Antibody
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特异性
- Manic Fringe Polyclonal Antibody detects endogenous levels of Manic Fringe protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human MFNG. AA range:61-110
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Manic Fringe (MFNG) (MFNG)
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别名
- MFNG
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背景
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Synonyms: MFNG, Beta-1, 3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Background: This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009],
Gene Name: MFNG
Protein Name: Beta-1,3-N-acetylglucosaminyltransferase manic fringe
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分子量
- 36 kDa
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基因ID
- 4242
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OMIM
- 602577
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UniProt
- O00587
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途径
- Notch Signaling
抗原
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