FADD 抗体 (pSer191)
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Quick Overview for FADD 抗体 (pSer191) (ABIN1450524)
抗原
See all FADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 157-206, pSer191
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原理
- FADD (phospho Ser191) Antibody
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特异性
- Phospho-FADD (S191) Polyclonal Antibody detects endogenous levels of FADD protein only when phosphorylated at S191.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from mouse FADD around the phosphorylation site of Ser191. AA range:157-206
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亚型
- IgG
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anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibody
FADD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 12-206) antibodyFADD 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 20-150) antibodyFADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5A6A2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 7-178) antibodyFADD 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD 适用: 小鼠 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal J1D2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) antibodyFADD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-80) antibodyFADD 适用: 小鼠 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (C-Term) antibodyFADD 适用: 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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别名
- FADD
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背景
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Synonyms: FADD, MORT1, GIG3, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity
Background: The Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Gene Name: FADD
Protein Name: Protein FADD
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分子量
- 23 kDa
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UniProt
- Q13158
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途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
抗原
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