Nkx2-2 抗体 (Middle Region)
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Quick Overview for Nkx2-2 抗体 (Middle Region) (ABIN1450127)
抗原
See all Nkx2-2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid synthetic peptide near the center of Human NKX2-2
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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别名
- NKX2-2
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背景
- NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature alpha-, beta- and PP cells, and in NKX2-2-null mice embryos, all beta-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.Synonyms: Homeobox protein Nkx-2.2, NK2 transcription factor related, NKX2.2, NKX2B, locus 2
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基因ID
- 4821
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NCBI登录号
- NP_002500
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途径
- Dopaminergic Neurogenesis
抗原
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