CARD10 抗体 (N-Term)
Quick Overview for CARD10 抗体 (N-Term) (ABIN1449965)
抗原
See all CARD10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid synthetic peptide near the amino terminus of human CARMA3
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 863-1032) antibody
CARD10 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (N-Term) antibodyCARD10 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) antibodyCARD10 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 341-600) antibodyCARD10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (AA 481-530) antibodyCARD10 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) antibodyCARD10 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 10 (CARD10) (Internal Region) antibodyCARD10 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
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别名
- CARD10 / CARMA3
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背景
- CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA3 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kB activation. When expressed in cells, this protein binds to BCL10 and activates NF-kB Recent experiments have shown that CARMA3 is required for EGF-induced NF-kB activation and contributes to tumor growth in vivo, suggesting that CARMA3 may serve as a new therapeutic target for the treatment of EGFR-driven tumors.Synonyms: BIMP1, CARD10, Caspase recruitment domain family member 10
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基因ID
- 29775
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NCBI登录号
- NP_055365
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途径
- S100 Proteins
抗原
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