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TTBK2 抗体 (C-Term)

TTBK2 适用: 人 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449960
发货至: 中国
  • 抗原 See all TTBK2 抗体
    TTBK2 (tau Tubulin Kinase 2 (TTBK2))
    抗原表位
    • 15
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    C-Term
    适用
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    宿主
    • 43
    • 3
    克隆类型
    • 45
    • 1
    多克隆
    标记
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    This TTBK2 antibody is un-conjugated
    应用范围
    • 42
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    • 7
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid synthetic peptide near the carboxy terminus of Human TTBK2
    亚型
    IgG
    Top Product
    Discover our top product TTBK2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TTBK2 (tau Tubulin Kinase 2 (TTBK2))
    别名
    TTBK2 (TTBK2 产品)
    别名
    ttbk antibody, MGC146331 antibody, 2610507N02Rik antibody, AI326283 antibody, B930008N24Rik antibody, TTK antibody, Ttbk antibody, Ttbk1 antibody, mKIAA0847 antibody, SCA11 antibody, TTBK antibody, tau tubulin kinase 2 antibody, TTBK2 antibody, ttbk2 antibody, Ttbk2 antibody
    背景
    Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins. Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11), a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib, and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib, suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance.Synonyms: KIAA0847, Tau-tubulin kinase 2
    基因ID
    146057
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