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TTBK2 抗体 (AA 1151-1244)

TTBK2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385629
发货至: 中国
  • 抗原 See all TTBK2 抗体
    TTBK2 (tau Tubulin Kinase 2 (TTBK2))
    抗原表位
    • 14
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 1151-1244
    适用
    • 46
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 43
    • 3
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TTBK2 antibody is un-conjugated
    应用范围
    • 41
    • 22
    • 20
    • 13
    • 12
    • 12
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TTBK2/SCA11
    亚型
    IgG
    Top Product
    Discover our top product TTBK2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    TTBK2 (tau Tubulin Kinase 2 (TTBK2))
    别名
    TTBK2/SCA11 (TTBK2 产品)
    别名
    ttbk antibody, MGC146331 antibody, 2610507N02Rik antibody, AI326283 antibody, B930008N24Rik antibody, TTK antibody, Ttbk antibody, Ttbk1 antibody, mKIAA0847 antibody, SCA11 antibody, TTBK antibody, tau tubulin kinase 2 antibody, TTBK2 antibody, ttbk2 antibody, Ttbk2 antibody
    背景

    Synonyms: TTBK2/SCA11 Tau tubulin kinase 2, Spinocerebellar ataxia 11, Tau tubulin kinase 2, Tau-tubulin kinase 2, TTBK, TTBK 2, TTBK1, TTBK2 , TTBK2_HUMAN, TTK, KIAA0847, mKIAA0847, SCA11.

    Background: SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.

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