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Nibrin 抗体 (N-Term)

Name: Nibrin 抗体 (N-Term)
SKU: ABIN1449929
Availability: OutOfStock

NBN 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of NIBRIN in rat lung tissue lysate with NIBRIN antibody (N-term) Cat. (Nibrin 抗体 (N-Term))

Immunohistochemistry of NIBRIN (NT) in human lung tissue with NIBRIN antibody (N-term) Cat. (Nibrin 抗体 (N-Term))

IHC (p)

2 images

产品编号 ABIN1449929

发货至: 中国

Datasheet as PDF

抗原 See all Nibrin (NBN) 抗体

Nibrin (NBN)
抗原表位
36

15

12

8

7

5

5

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
98

59

35

2

1

1

1

1
人, 小鼠, 大鼠
宿主
115

15
兔
Compatible Secondaries
克隆类型
106

24
多克隆
标记
64

8

6

6

6

6

6

6

5

3

2

2

2

2

2

2

2
This Nibrin antibody is un-conjugated
应用范围
101

45

27

26

26

26

22

17

9

8

6

3

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

交叉反应（详细）

Species reactivity (tested):Human, Mouse, Rat.

纯化方法

Affinity chromatography purified via peptide column

免疫原

16 amino acid synthetic peptide near the amino terminus of Human NIBRIN

亚型

IgG

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NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated

anti-Nibrin (NBN) (AA 435-754) antibody
NBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 645-754) antibody
NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS containing 0.02 % Sodium Azide as preservative

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

Nibrin (NBN)

别名

Nibrin (NBN 产品)

别名

NBN antibody, AT-V1 antibody, AT-V2 antibody, ATV antibody, NBS antibody, NBS1 antibody, P95 antibody, Nbs1 antibody, im:6911679 antibody, zgc:194152 antibody, nibrin antibody, NBN antibody, nbn antibody, Nbn antibody

背景

NIBRIN (NBN) is a member of the double-strand break repair complex MRE11/RAD50/NBN (MRN) which is involved in DNA double-strand break repair, DNA damage-induced checkpoint activation and plays a critical role in the maintenance of chromosome integrity. NIBRIN contains two modules found in cell cycle checkpoint proteins, a forkhead-associated domain adjacent to a breast cancer carboxy-terminal domain. Mutations in this gene are associated with Nijmegen breakage syndrome and maybe the cause of cancer predisposition and aplastic anemia.Synonyms: Cell cycle regulatory protein p95, NBN, NBS, NBS1, Nijmegen breakage syndrome protein 1, P95

基因ID

4683

NCBI登录号

NP_002476

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response