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Nibrin 抗体 (N-Term)

This anti-Nibrin antibody is a 兔 多克隆 antibody detecting Nibrin in WB, IF, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1449929
发货至: 中国

Quick Overview for Nibrin 抗体 (N-Term) (ABIN1449929)

抗原

See all Nibrin (NBN) 抗体
Nibrin (NBN)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 98
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多克隆

标记

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This Nibrin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid synthetic peptide near the amino terminus of Human NIBRIN

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Nibrin (NBN)

    别名

    Nibrin

    背景

    NIBRIN (NBN) is a member of the double-strand break repair complex MRE11/RAD50/NBN (MRN) which is involved in DNA double-strand break repair, DNA damage-induced checkpoint activation and plays a critical role in the maintenance of chromosome integrity. NIBRIN contains two modules found in cell cycle checkpoint proteins, a forkhead-associated domain adjacent to a breast cancer carboxy-terminal domain. Mutations in this gene are associated with Nijmegen breakage syndrome and maybe the cause of cancer predisposition and aplastic anemia.Synonyms: Cell cycle regulatory protein p95, NBN, NBS, NBS1, Nijmegen breakage syndrome protein 1, P95

    基因ID

    4683

    NCBI登录号

    NP_002476

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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