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Integrin beta 3 抗体

ITGB3 适用: 小鼠 WB, FACS, IP 宿主: 大鼠 Monoclonal 1-55-4 unconjugated
产品编号 ABIN1449278
发货至: 中国
  • 抗原 See all Integrin beta 3 (ITGB3) 抗体
    Integrin beta 3 (ITGB3)
    适用
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    小鼠
    宿主
    • 118
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    大鼠
    克隆类型
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    单克隆
    标记
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    This Integrin beta 3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    交叉反应 (详细)
    Species reactivity (tested):Mouse. Not Human (PBCM cells on Flow cytometry).
    纯化方法
    Protein G agarose
    免疫原
    Mouse platelet
    克隆位点
    1-55-4
    亚型
    IgG2a
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    Integrin beta 3 (ITGB3)
    别名
    CD61 / ITGB3 (ITGB3 产品)
    别名
    BDPLT16 antibody, BDPLT2 antibody, CD61 antibody, GP3A antibody, GPIIIa antibody, GT antibody, INGRB3 antibody, integrin antibody, INTB3 antibody, GPIIIA antibody, cd61 antibody, gp3a antibody, itgb3 antibody, itgb3.2 antibody, itgb3.1 antibody, integrin subunit beta 3 antibody, integrin beta 3 antibody, integrin subunit beta 3 L homeolog antibody, integrin beta 3a antibody, integrin beta 3b antibody, ITGB3 antibody, Itgb3 antibody, itgb3.L antibody, itgb3a antibody, itgb3b antibody
    背景
    Platelet activation results in a conformational change of the membrane spanning platelet integrin GPIIb/IIIa (aIIbß3, CD41/CD61) enabling the binding of the plasma protein fibrinogen. This binding is primarily reversible, but it enhances platelet activation by outside-in signal causing receptor clustering, platelet secretion, and finally irreversible fibrinogen binding and platelet aggregation.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
    基因ID
    10090
    UniProt
    O54890
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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