Integrin beta 3 抗体
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- 抗原 See all Integrin beta 3 (ITGB3) 抗体
- Integrin beta 3 (ITGB3)
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Integrin beta 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
- 交叉反应 (详细)
- Species reactivity (tested):Mouse. Not Human (PBCM cells on Flow cytometry).
- 纯化方法
- Protein G agarose
- 免疫原
- Mouse platelet
- 克隆位点
- 1-55-4
- 亚型
- IgG2a
- Top Product
- Discover our top product ITGB3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- 抗原
- Integrin beta 3 (ITGB3)
- 别名
- CD61 / ITGB3 (ITGB3 产品)
- 背景
- Platelet activation results in a conformational change of the membrane spanning platelet integrin GPIIb/IIIa (aIIbß3, CD41/CD61) enabling the binding of the plasma protein fibrinogen. This binding is primarily reversible, but it enhances platelet activation by outside-in signal causing receptor clustering, platelet secretion, and finally irreversible fibrinogen binding and platelet aggregation.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
- 基因ID
- 10090
- UniProt
- O54890
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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