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Integrin beta 3 抗体

ITGB3 适用: 小鼠 WB, FACS, IP 宿主: 大鼠 Monoclonal 1-55-4 unconjugated
产品编号 ABIN1449278
发货至: 中国
  • 抗原 See all Integrin beta 3 (ITGB3) 抗体
    Integrin beta 3 (ITGB3)
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This Integrin beta 3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    交叉反应 (详细)
    Species reactivity (tested):Mouse. Not Human (PBCM cells on Flow cytometry).
    纯化方法
    Protein G agarose
    免疫原
    Mouse platelet
    克隆位点
    1-55-4
    亚型
    IgG2a
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    Integrin beta 3 (ITGB3)
    别名
    CD61 / ITGB3 (ITGB3 产品)
    背景
    Platelet activation results in a conformational change of the membrane spanning platelet integrin GPIIb/IIIa (aIIbß3, CD41/CD61) enabling the binding of the plasma protein fibrinogen. This binding is primarily reversible, but it enhances platelet activation by outside-in signal causing receptor clustering, platelet secretion, and finally irreversible fibrinogen binding and platelet aggregation.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
    基因ID
    10090
    UniProt
    O54890
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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