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CD59 抗体 (FITC)

CD59 适用: 人 FACS 宿主: 小鼠 Monoclonal WK8 FITC
产品编号 ABIN1449270
发货至: 中国
  • 抗原 See all CD59 抗体
    CD59
    适用
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    宿主
    • 87
    • 68
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    小鼠
    克隆类型
    • 93
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    单克隆
    标记
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    This CD59 antibody is conjugated to FITC
    应用范围
    • 97
    • 69
    • 46
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    • 14
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with human CD59 antigen.
    纯化方法
    Protein A agarose
    免疫原
    Human myeloma cell line (RPMI8226)
    克隆位点
    WK8
    亚型
    IgG2b
    Top Product
    Discover our top product CD59 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS containing 1 % BSA and 0.09 % NaN3
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原
    CD59
    别名
    CD59 (CD59 产品)
    别名
    16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
    背景
    CD59, an 18-20 kDa GPI-anchored glycoprotein, is broadly distributed, present in most tissues, and on all circulating cells. CD59 has been also known as 20 kDa homologous restriction factor (HRF20), membrane attack complex inhibitory factor (MACIF), membrane inhibitor of reactive lysis (MIRL) and protectin. CD59 inhibits the cytolytic activity of complement by binding to C8 and C9 in the assembling of the cytolytic membrane attack complex (MAC), thereby interfering with membrane insertion and pore formation. CD59 and other membrane complement regulatory proteins (CD46 and CD55) are frequently overexpressed on cancer cells, possibly as a mechanism for cancer cells to overcome lysis by complement. CD59 also interacts with T cell-restricted glycoprotein CD2 and plays a role in T cell activation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
    基因ID
    966
    NCBI登录号
    NP_000602
    UniProt
    P13987
    途径
    Complement System
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