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KPNB1 抗体

This anti-KPNB1 antibody is a 大鼠 单克隆 antibody detecting KPNB1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1449199
发货至: 中国

Quick Overview for KPNB1 抗体 (ABIN1449199)

抗原

See all KPNB1 抗体
KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 47
  • 4
  • 1
大鼠

克隆类型

  • 48
  • 4
单克隆

标记

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  • 3
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KPNB1 antibody is un-conjugated

应用范围

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  • 13
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  • 9
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  • 5
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  • 1
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Western Blotting (WB)

克隆位点

1D7
  • 特异性

    This antibody detects Importin β.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein G agarose

    免疫原

    Recombinant full-length mouse importin beta

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

    别名

    NTF97

    背景

    Importin ß (karyopherin ß/PTAC97) forms a complex with importin a that is required for classical import of proteins across the nuclear envelope through the nuclear pore complex. Importin a acts as a bridge between the nuclear localization sequence (NLS) and importin ß, while importin ß is the site of initial docking to the pore and is responsible for transport of the target protein into the nucleus. Inside the nucleus, Ran-GTP binds to importin ß, resulting in dissociation of the ternary complex, and importin a and ß are independently recycled back into the cytoplasm. Recently some NLS-containing proteins have been shown to bind directly to importin ß and enter the nucleus in an importin a independent manner.Synonyms: Importin subunit beta-1, Importin-90, KPNB1, Nuclear factor P97

    分子量

    96 kDa

    基因ID

    3837

    NCBI登录号

    NP_002256

    UniProt

    Q14974

    途径

    Protein targeting to Nucleus
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