ABI1 抗体
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Quick Overview for ABI1 抗体 (ABIN1449186)
抗原
See all ABI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with Abi-1.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Hamster
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纯化方法
- Protein A agarose
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免疫原
- Human recombinant Abi-1 expressed in E. coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- ABI1 (Abl-Interactor 1 (ABI1))
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别名
- ABI1 / SSH3BP1
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背景
- Abl interactor (Abi) proteins are c-Abl-binding proteins that bind to both the Src homology 3 (SH3) domain and the C-terminal proline-rich regions of Abl kinase through dual SH3-PXXP interactions. Two highly related genes, abi-1 and abi-2, were cloned. In addition to the interaction with Abl kinase, Abi proteins also interact with other signaling molecules. Recently, it has been reported that Abi-1 dramatically promoted c-Abl-mediated tyrosine (Tyr296) phosphorylation of Mena [mammalian homologue of Drosophila Enabled (Ena)] by interacting with both proteins.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1
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分子量
- 65 kDa
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基因ID
- 10006
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NCBI登录号
- NP_001012768
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UniProt
- Q8IZP0
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途径
- RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
抗原
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