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ABI1 抗体

This 小鼠 单克隆 anti-ABI1 antibody (Clone 1B9) specifically detects ABI1 in WB, IP 和 IHC (p). The antibody is reactive with 人, 小鼠 和 Hamster samples.
产品编号 ABIN1449186
发货至: 中国
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Quick Overview for ABI1 抗体 (ABIN1449186)

抗原

See all ABI1 抗体
ABI1 (Abl-Interactor 1 (ABI1))

适用

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人, 小鼠, Hamster

宿主

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小鼠

克隆类型

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单克隆

标记

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This ABI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1B9
  • 特异性

    This antibody reacts with Abi-1.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Hamster

    纯化方法

    Protein A agarose

    免疫原

    Human recombinant Abi-1 expressed in E. coli

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    ABI1 (Abl-Interactor 1 (ABI1))

    别名

    ABI1 / SSH3BP1

    背景

    Abl interactor (Abi) proteins are c-Abl-binding proteins that bind to both the Src homology 3 (SH3) domain and the C-terminal proline-rich regions of Abl kinase through dual SH3-PXXP interactions. Two highly related genes, abi-1 and abi-2, were cloned. In addition to the interaction with Abl kinase, Abi proteins also interact with other signaling molecules. Recently, it has been reported that Abi-1 dramatically promoted c-Abl-mediated tyrosine (Tyr296) phosphorylation of Mena [mammalian homologue of Drosophila Enabled (Ena)] by interacting with both proteins.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1

    分子量

    65 kDa

    基因ID

    10006

    NCBI登录号

    NP_001012768

    UniProt

    Q8IZP0

    途径

    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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