ZNRF3 抗体 (PE-Cy5)
Quick Overview for ZNRF3 抗体 (PE-Cy5) (ABIN1434639)
抗原
See all ZNRF3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠, 小鸡, 犬, 猪, 牛
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纯化方法
- purified by Protein A
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免疫原
- KLH conjugated synthetic peptide derived from human ZNRF3
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亚型
- IgG
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说明
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Excitation / Emission wavelength: 496nm / 556nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 µg/µL
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4 °C for 12 months
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有效期
- 12 months
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- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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别名
- ZNRF3
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背景
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF3 (Zinc/RING finger protein 3), also known as RNF203 (RING finger protein 203), is a 936 amino acid single pass transmembrane protein that contains one RING-type zinc finger. Related zinc/RING finger proteins, such as ZNRF1 and ZNRF2, are E3 ubiquitin-protein ligases that are thought to be involved in the establishment and maintenance of neuronal transmission and plasticity, therefore it is likely that ZNRF3 may function in a similar manner.
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基因ID
- 84133
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HGNC
- 0
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途径
- WNT signaling
抗原
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