P2RY14 抗体 (PE)
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北京 101111
Quick Overview for P2RY14 抗体 (PE) (ABIN1429375)
抗原
See all P2RY14 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GPR105 Polyclonal Antibody, PE Conjugated
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预测反应
- Human,Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105
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亚型
- IgG
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anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) antibody
P2RY14 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5A3F1 unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (2nd Extracellular Loop), (AA 172-188) antibodyP2RY14 适用: 人 WB, IHC, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (AA 209-338) antibodyP2RY14 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (AA 17-338) antibodyP2RY14 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (AA 51-303) antibodyP2RY14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (2nd Extracellular Loop), (AA 172-188) antibody (FITC)P2RY14 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (AA 209-338) antibodyP2RY14 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) antibodyP2RY14 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (Internal Region) antibodyP2RY14 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14) (AA 146-195) antibodyP2RY14 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- P2RY14 (Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14))
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别名
- Gpr105
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背景
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Synonyms: A330108O13Rik, G protein coupled receptor for UDP-glucose, G protein-coupled receptor 105, G protein-coupled receptor VTR 15-20, G-protein coupled receptor 105, GPR105, KIAA0001, P2RY14, P2Y purinoceptor 14, P2Y14 receptor, P2Y14, P2Y14 receptor, P2Y14_HUMAN, Purinergic receptor P2Y G protein coupled 14, Similar to TYPE-1 Angiotensin II receptor, UDP-glucose receptor, GPCR GPR105.
Background: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR105, also designated P2Y14, is widely expressed throughout many brain regions where it localizes to glial cells, and specifically co-localizes with astrocytes. GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function.
抗原
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