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P2RY14 抗体 (PE)

This anti-P2RY14 antibody is a 兔 多克隆 antibody detecting P2RY14 in FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1429375
发货至: 中国

Quick Overview for P2RY14 抗体 (PE) (ABIN1429375)

抗原

See all P2RY14 抗体
P2RY14 (Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14))

适用

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人, 小鼠, 大鼠

宿主

  • 45
  • 3

克隆类型

  • 45
  • 3
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
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  • 1
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This P2RY14 antibody is conjugated to PE

应用范围

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  • 9
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Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105

    亚型

    IgG
  • 应用备注

    FCM(1:20-100)

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4°C

    有效期

    12 months
  • 抗原

    P2RY14 (Purinergic Receptor P2Y, G-Protein Coupled, 14 (P2RY14))

    别名

    Gpr105

    背景

    G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR105, also designated P2Y14, is widely expressed throughout many brain regions where it localizes to glial cells, and specifically co-localizes with astrocytes. GPR105 is upregulated when a tissue is immunologically challenged with lipopolysaccharide, leading to the theory that GPR105 may play an important role in modulating peripheral and neuroimmune function.

    Subcellular location: Extracellular


    Synonyms: A330108O13Rik, G protein coupled receptor for UDP-glucose, G protein-coupled receptor 105, G protein-coupled receptor VTR 15-20, G-protein coupled receptor 105, GPR105, KIAA0001, P2RY14, P2Y purinoceptor 14, P2Y14 receptor, P2Y14, P2Y14 receptor, P2Y14_HUMAN, Purinergic receptor P2Y G protein coupled 14, Similar to TYPE-1 Angiotensin II receptor, UDP-glucose receptor, GPCR GPR105.
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