TSEN2 抗体 (Cy3)
Quick Overview for TSEN2 抗体 (Cy3) (ABIN1422227)
抗原
See all TSEN2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TSEN2
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亚型
- IgG
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anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibody
TSEN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-220) antibodyTSEN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-465) antibodyTSEN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 1-220) antibodyTSEN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (AA 395-444) antibodyTSEN2 适用: 人, 犬, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) antibodyTSEN2 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
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别名
- TSEN2
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背景
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Synonyms: HsSen2, MGC2776, MGC4440, SEN2, SEN2L, tRNA intron endonuclease Sen2, tRNA splicing endonuclease 2 homolog SEN2, S. cerevisiae, tRNA splicing endonuclease subunit Sen2, TSEN 2, SEN2_HUMAN.
Background: The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5? and 3? splice sites, thereby releasing introns and free tRNA molecules with 2',3' cyclic phosphates and 5'-OH termini. In addition to its role in pre-tRNA splicing, the heterotetrameric endonuclease complex participates in mRNA processing and, via its association with pre-mRNA processing factors, is thought to link pre-tRNA and pre-mRNA splicing events. TSEN2 (tRNA-splicing endonuclease subunit Sen2), also known as tRNA-intron endonuclease Sen2, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex. There are three isoforms of TSEN2 that are produced as a result of alternative splicing events. Isoform 1 seems to carry the active site for 5?-splice site cleavage. Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, which is characterized by progressive microencephaly with epilepsy, extrapyramidal dyskinesia and chorea without spinal cord findings.
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基因ID
- 80746
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途径
- Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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