ZNRF3 抗体 (AA 120-165) (Cy3)
Quick Overview for ZNRF3 抗体 (AA 120-165) (Cy3) (ABIN1418939)
抗原
See all ZNRF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-165
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ZNRF3
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亚型
- IgG
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anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 120-165) antibody
ZNRF3 适用: 人, 小鼠, 大鼠 IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc and Ring Finger Protein 3 (ZNRF3) (AA 56-219) antibodyZNRF3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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别名
- ZNRF3
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背景
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Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133
Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
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基因ID
- 84133
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UniProt
- Q9ULT6
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途径
- WNT signaling
抗原
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