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O3FAR1 抗体 (AA 21-120) (Cy5.5)

This anti-O3FAR1 antibody is a 兔 多克隆 antibody detecting O3FAR1 in WB, IF (cc) 和 IF (p). Suitable for 人 和 小鼠.
产品编号 ABIN1417813
发货至: 中国

Quick Overview for O3FAR1 抗体 (AA 21-120) (Cy5.5) (ABIN1417813)

抗原

See all O3FAR1 抗体
O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

适用

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人, 小鼠

宿主

  • 62
  • 1
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克隆类型

  • 63
  • 1
多克隆

标记

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This O3FAR1 antibody is conjugated to Cy5.5

应用范围

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  • 26
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 21-120

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human G protein coupled receptor 120

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

    别名

    GPR120

    背景

    Synonyms: G protein coupled receptor 120, GPCR GPR120, G protein coupled receptor 129, G protein coupled receptor GT01, G protein coupled receptor PGR 4, G protein coupled receptor PGR4, G-protein coupled receptor 120, G-protein coupled receptor 129, G-protein coupled receptor GT01, G-protein coupled receptor PGR4, GPR 120, GPR 129, GPR120, GPR129, GT01, HGNC:19345, MGC119984, O3FA1_HUMAN, O3FAR1, Omega-3 fatty acid receptor 1, PGR 4, PGR4, GPCR120.

    Background: GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.

    基因ID

    338557

    UniProt

    Q5NUL3

    途径

    Hormone Transport
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