TFAM 抗体 (AA 155-246) (Cy7)
Quick Overview for TFAM 抗体 (AA 155-246) (Cy7) (ABIN1417394)
抗原
See all TFAM 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 155-246
-
交叉反应
- 小鼠, 大鼠
-
预测反应
- Human,Dog,Cow,Sheep,Pig,Rabbit,Goat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human MtTF1
-
亚型
- IgG
-
-
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
-
别名
- MtTF1
-
背景
-
Synonyms: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, TCF-6, Transcription factor 6-like 2, TFAM
Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
-
基因ID
- 7019
-
UniProt
- Q00059
-
途径
- Chromatin Binding
抗原
-