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PEN2 抗体 (AA 6-80) (Cy3)

This Cy3-conjugated 兔 多克隆 anti-PEN2 antibody specifically detects PEN2 in WB, IF (cc) 和 IF (p). The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN1415266
发货至: 中国
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Quick Overview for PEN2 抗体 (AA 6-80) (Cy3) (ABIN1415266)

抗原

See all PEN2 (PSENEN) 抗体
PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

适用

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  • 37
  • 5
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  • 4
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  • 2
  • 2
  • 1
  • 1
小鼠, 大鼠

宿主

  • 48
  • 3

克隆类型

  • 29
  • 22
多克隆

标记

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  • 4
  • 2
  • 2
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  • 2
  • 2
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  • 2
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  • 1
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This PEN2 antibody is conjugated to Cy3

应用范围

  • 39
  • 15
  • 13
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  • 11
  • 11
  • 6
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-80

    特异性

    Belongs to the PEN-2 family

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PEN2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

    别名

    PEN2

    背景

    Synonyms: PEN2, PEN-2, MDS033, MSTP064, Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

    基因ID

    55851

    UniProt

    Q9NZ42

    途径

    Notch Signaling, Neurotrophin Signaling Pathway
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